Dr. Mukherjee is a computational chemist with a research interest in biophysical systems and processes. A core focus of the Saumyak Mukherjee Research Group (SMRG) is liquid-liquid phase separation of biomolecules and the properties of biocondensates. By combining molecular simulations, statistical mechanics, and machine learning, the group studies the structure, dynamics, and thermodynamics of biomolecules — from individual proteins, lipids, and nucleic acids to the larger assemblies they form and the processes they drive.
- Yang, Mukherjee, et al. SND3 is the membrane insertase within a fungal multipass translocon. Nat. Commun. 2025, 16, 9566.
- Mukherjee et al. Heterogeneous Slowdown of Dynamics in the Condensate of an Intrinsically Disordered Protein. J. Phys. Chem. Lett. 2024, 15, 11244−11251.
- Mukherjee et al. Thermodynamic Forces from Protein and Water Govern Condensate Formation of an Intrinsically Disordered Protein Domain. Nat. Commun. 2023, 14, 5892.
- Mukherjee et al. Tug-of-War between Internal and External Frictions and Viscosity Dependence of Rate in Biological Reactions. Phys. Rev. Lett. 2022, 128, 108101.
- Mukherjee et al. Mechanism of Solvent Control of Protein Dynamics. Phys. Rev. Lett. 2019, 122, 058101.
- Mukherjee et al. What Gives an Insulin Hexamer Its Unique Shape and Stability? Role of Ten Confined Water Molecules. J. Phys. Chem. B 2018, 122, 1631–1637.
- Mukherjee et al. Distinguishing Dynamical Features of Water inside Protein Hydration Layer: Distribution Reveals what is Hidden Behind the Average. J. Chem. Phys. 2017, 147, 024901.
